• Ain Shams MS unit was established in 2013 serving more than 3500 patients. The unit features two Day-Care rooms with 7 beds in addition to its outpatient clinic.
MS Registry:
• Full registration of all MS patients encountered with medical number and ID
• Both hard copies and electronic medical records are implemented including the international MS-BASE and Egypt MS Network.
Training, continuous medical education and scientific activities
Achievements:
• The Ain-Shams MS unit has the largest local registry in Egypt with more than 3700 cases with full documentation.
• Egypt is ranked number 7 in the patient enrollment by country in the largest international MS register (MSBase) with 80% cases from Ain Shams.
• The unit took part in several international phase III trials. It is the only MS unit in Egypt to participate in all phase III trials in which Egypt participated in.
• Ain Shams MS unit signed a cooperation protocol with the National Health Insurance and played a major role in achieving full governmental imbursement of Interferons, Fingolimod, Teriflunomide, Rituximab, Ocrelizumab and Dimethyl Fumarate.
• Dr Magd Zakaria is the first neurologist from Egypt to publish in the multiple sclerosis and related disorders (MSARD) journal (which is one of the top journals in the field), and his first article was awarded as editor’s choice.
• He later published many article in these journals and became member of the editorial board. He was also the only one from Egypt to be chosen in the board of the following prestigious international societies: MENACTRIMS, Brain Health Organization, Multiple Sclerosis Global Advisory Network (MSGAN), international medical and scientific board (IMSB) of the multiple sclerosis, and Multiple sclerosis International Federation (MSIF). In addition, he was the only invited speaker form the Middle East in the biggest international MS conference (ECTRIMS) which was held in Stockholm, 2019.
Vision & Mission
Education
Clinical Services
• Thorough medical and neurological assessment including EDSS rating
• Detailed revision and documentation of patient investigations
• Prophylactic and relapse treatment plans tailored for each MS patient implemented under supervision of unit’s highly specialized staff
• Management of complications and associated symptoms through a multidisciplinary team in different specialties
• Continuous follow up and documentation of patient’s condition and new events
• Patient and community awareness (one on one in regular, community events and patient support group meetings and online)
• Liaison Medication
• The outpatient clinic works 5 days per week (Saturday-Sunday-Monday-Tuesday-Wednesday) and serving an average of 800 patients per month, and is responsible for around 300-400 state funded reports monthly
• The day care serves around 300 patients per month
Community Services
Fellowships and Observerships
National and International Collaboration
Publications
1. Pregnancy and the use of disease-modifying therapies in patients with multiple sclerosis: benefits versus risks
Raed Alroughani, Ayse Altintas, Mohammed Al Jumah, Mohammadali Sahraian, Issa Alsharoqi, Abdurahman AlTahan, Abdulkader Daif, Maurice Dahdaleh, Dirk Deleu, Oscar Fernandez, Nikolaos Grigoriadis, Jihad Inshasi, Rana Karabudak, Karim Taha, Natalia Totolyan, Bassem I Yamout, Magd Zakaria, Saeed Bohlega
Multiple sclerosis international, 2016
2. Consensus guidelines for the diagnosis and treatment of multiple sclerosis
B Yamout, R Alroughani, M Al-Jumah, S Khoury, N Abouzeid, M Dahdaleh, I Alsharoqi, J Inshasi, S Hashem, M Zakaria, K ElKallab, T Alsaadi, T Tawfeek, S Bohlega
Current medical research and opinion 29 (6), 611-621, 2013
3. Consensus recommendations for the diagnosis and treatment of multiple sclerosis: the Middle East North Africa Committee for Treatment and Research in Multiple Sclerosis …
B Yamout, R Alroughani, M Al-Jumah, R Goueider, M Dahdaleh, J Inshasi, S Hashem, I Alsharoqi, M Sahraian, S Khoury, Z Alkawi, S Koussa, M Zakaria, J Al Khaburi, T Alsaadi, S Bohlega
Current Medical Research and Opinion 31 (7), 1349-1361, 2015
4. Smoke and mirrors: limited value of relative risk reductions for assessing the benefits of disease-modifying therapies for multiple sclerosis
M Zakaria
Multiple Sclerosis and Related Disorders 4 (3), 187-191, 2015
5. International consensus on quality standards for brain health-focused care in multiple sclerosis
Jeremy Hobart, Amy Bowen, George Pepper, Harriet Crofts, Lucy Eberhard, Thomas Berger, Alexey Boyko, Cavit Boz, Helmut Butzkueven, Elisabeth Gulowsen Celius, Jelena Drulovic, José Flores, Dana Horakova, Christine Lebrun-Frénay, Ruth Ann Marrie, James Overell, Fredrik Piehl, Peter Vestergaard Rasmussen, Maria José Sa, Carmen-Adella Sîrbu, Eli Skromne, Oivind, Torkildsen, Vincent Van Pesch, Timothy Vollmer, Magd Zakaria, Tjalf Ziemssen, Gavin Giovannoni
Multiple Sclerosis Journal 25 (13), 1809-1818, 2019
6. Clinical characteristics of patients with multiple sclerosis enrolled in a new registry in Egypt
Magd Zakaria, Dina A Zamzam, Mohamed A Abdel Hafeez, Mahmoud S Swelam, Shaimaa S Khater, Mai F Fahmy, Ayman Abdel Hady, Mohamed M Fouad, Azza Abdel Nasser, Hany Aref, Mohsen Gadallah
Multiple sclerosis and related disorders 10, 30-35, 2016
7. Characteristics of multiple sclerosis in the Middle East with special reference to the applicability of international guidelines to the region
Abdulrahman M Al Tahan, Isa Alsharoqi, Saeed A Bohlega, Maurice Dahdaleh, Abdulkader Daif, Dirk Deleu, Khaled Esmat, Dominic Giampaolo, Mark S Freedman, Michael Gwilt, Hassan Hosny, Jihad S Inshasi, Mohammed Aljumah, Ahmad Khalifa, Hossein Pakdaman, Miklos Szolics, Bassem I Yamout, Mohammed A Sahraian, Magd F Zakaria
International Journal of Neuroscience 124 (9), 635-641, 2014
8. Intervening to reduce the risk of future disability from multiple sclerosis: are we there yet?
Maurice Dahdaleh, Raed Alroughani, Mohammed Aljumah, Abdulrahman AlTahan, Issa Alsharoqi, Saeed A Bohlega, Abdulkader Daif, Dirk Deleu, Jihad Inshasi, Rana Karabudak, Mohammed A Sahraian, Karim Taha, Bassem I Yammout, Magd Zakaria
International Journal of Neuroscience 127 (10), 944-951, 2017
9. Consensus recommendations for the diagnosis and treatment of multiple sclerosis: 2019 revisions to the MENACTRIMS guidelines
B Yamout, M Sahraian, S Bohlega, M Al-Jumah, R Goueider, M Dahdaleh, J Inshasi, S Hashem, I Alsharoqi, S Khoury, M Alkhawajah, S Koussa, J Al Khaburi, A Almahdawi, T Alsaadi, E Slassi, S Daodi, M Zakaria, R Alroughani
Multiple sclerosis and related disorders 37, 101459, 2020
10. Vitamin D and body mass index in Egyptian multiple sclerosis patients
Dina Zamzam, Mohamed Foad, Mahmoud Swelam, Mohamed AbdelHafez, Azza AbdelNasser, Ramy Mahmoud, Hany Aref, Magd Zakaria
Multiple sclerosis and related disorders 28, 313-316, 2019
11. Immune Reconstitution Therapy or Continuous Immunosuppression for the Management of Active Relapsing–Remitting Multiple Sclerosis Patients? A Narrative Review
Isa Ahmed AlSharoqi, Mohamed Aljumah, Saeed Bohlega, Cavit Boz, Abdelkader Daif, Salam El-Koussa, Jihad Inshasi, Murat Kurtuncu, Thomas Müller, Chris Retief, Mohammad Ali Sahraian, Vahid Shaygannejad, Ilham Slassi, Karim Taha, Magd Zakaria, Per Soelberg Sorensen
Neurology and Therapy 9 (1), 55, 2020
12. Early Cognitive Impairment in Multiple Sclerosis Patients In Relation To Brain Atrophy, Egyptian Sample
MF Zakaria, TA Abdo, AA Abdelaziz, DA Zamzam, YA Abdullah, AM Abousteit
QJM: An International Journal of Medicine 113 (Supplement_1), hcaa054. 008, 2020
13. Economic Burden of Multiple Sclerosis in Egypt: A Societal Perspective
M Zakaria, M Sharawy, I Anan
Multiple Sclerosis and Related Disorders 37, 2020
14. A Multicenter International Study to Evaluate Different Aspects of Relationship between MS and Pregnancy
Ayse Altintas, Magd Zakaria, Raed Alroughani, Abdorreza Naser Moghadasi, Murat Terzi, Sedat Şen, Mesrure Koseoglu, Husnu Efendi, Aysun Soysal, Gokcen Gozubatik-Celik
Multiple Sclerosis and Related Disorders 37, 2020
15. Magnetic resonance imaging markers of disability in Egyptian multiple sclerosis patients
Mohamed A Abdelhafeez, Dina A Zamzam, Mohamed M Foad, Mahmoud S Swelam, Azza Abdelnasser, Hany A Aref, Yosra A Ibrahim, Nivan H Khater, Eman A Darwish, Magd F Zakaria
Multiple Sclerosis and Related Disorders 36, 101417, 2019
16. A multicenter international study to evaluate different aspects of relationship between MS and pregnancy
A Altintas, M Zakaria, R Alroughani, AN Moghadasi, M Terzi, S Sen, M Koseoglu, H Efendi, A Soysal, G Gozubatik-Celik, M Ozturk, M Sahraian, Y Akinci, ZE Kaya, S Saip, A Siva, M Gonen
MULTIPLE SCLEROSIS JOURNAL 25, 176-177, 2019
17. Economic Burden of Multiple Sclerosis in Egypt–A Societal Perspective (P4. 2-089)
M Zakaria, M Sharawy, M Raed, I Anan
Neurology 92 (15 Supplement), P4. 2-089, 2019
18. Real World Retrospective Study of Effectiveness and Safety of Fingolimod in Relapsing Remitting Multiple Sclerosis in the Middle East and North Africa (FINOMENA)
R Al Roughani, H Elfadally, H Al Otaiby, A Hasan, Z Al Kawi, MF Belahsen, MF Zakaria, M Khoury, M Harb, T Al Sadi, A Al Asmi
Multiple sclerosis and related disorders 26, 254, 2018
19. Radiological characteristics of patients with multiple sclerosis in Egypt
M AbdelHafeez, D Zamzam, M Swelam, A Abousteit, M Foad, A AbdelNasser, H Aref, Y Abdel-Zaher, N Khater, E Darwish, S Khater, M Zakaria
MULTIPLE SCLEROSIS JOURNAL 24, 852-852, 2018
20. Vitamin D and body mass index in Egyptian multiple sclerosis patients
D Zamzam, M Foad, M Swelam, M Abdelhafez, A Abdelnasser, R Mahmoud, H Aref, M Zakaria
MULTIPLE SCLEROSIS JOURNAL 24, 842-843, 2018
21. Highlights on cyclophosphamide effect in active relapsing-remitting multiple sclerosis
Magd Fouad Zakaria, Mahmoud Saad Swelam, Dina AbdEl-Gawad Zamzam, Ayman Mohamed Nasef, Samia Ashor Helal, Mohamed Aly Abdel Hafeez, Alaa Mohamed Abou Steit, Shaimaa Sayed Khater, Mohamad Mahmoud Fouad, Ayman Abdel Hady, Mohamed Hamdi Attia
MULTIPLE SCLEROSIS JOURNAL 24 (2), NP27-NP28, 2018
22. Clinical and radiological patterns of multiple sclerosis among a sample of Egyptian patients
Magd Foad Zakaria, Mohmmed Aly Abd Elhafeez, Dina Abd Elgawad Zamzam, Hala Mahmoud Elkhawas, Azza Abd Elnasser Abd El Aziz, Samia Ashor Mohammad, Samia Ashor Mohammad, Mahmoud Saad Swelam, Mohammad Foad, Hany Amin Aref
MULTIPLE SCLEROSIS JOURNAL 22 (6), NP17-NP17, 2016
23. Are DMDs really more effective in CIS. M Zakaria. Multiple sclerosis and related disorders 3 (6), 769, 2014
